Baihui

Acupoint name	Acupoint number	Target	Uniprot	References
Baihui	GV20	GFAP	Uniprot link	[1]
Baihui	GV20	EGFR	Uniprot link	[1]
Baihui	GV20	RNF125	Uniprot link	[1]
Baihui	GV20	IL31RA	Uniprot link	[1]
Baihui	GV20	GRIN3A	Uniprot link	[2]
Baihui	GV20	APP	Uniprot link	[3]
Baihui	GV20	DLG4	Uniprot link	[4]
Baihui	GV20	GRIA1	Uniprot link	[4]
Baihui	GV20	GRIN2B	Uniprot link	[4]
Baihui	GV20	TRAPPC12	Uniprot link	[5]
Baihui	GV20	CTSD	Uniprot link	[5]
Baihui	GV20	DYNC2LI1	Uniprot link	[5]
Baihui	GV20	PRKAG3	Uniprot link	[6]
Baihui	GV20	BECN2	Uniprot link	[6]
Baihui	GV20	GABARAPL2	Uniprot link	[6]
Baihui	GV20	IL6	Uniprot link	[6-11]
Baihui	GV20	IL18	Uniprot link	[6-7,12]
Baihui	GV20	TNF	Uniprot link	[6,8-9,11-18]
Baihui	GV20	PIK3C3	Uniprot link	[6]
Baihui	GV20	TRIM16	Uniprot link	[6]
Baihui	GV20	NOS3	Uniprot link	[19]
Baihui	GV20	RPH3AL	Uniprot link	[19]
Baihui	GV20	IL1B	Uniprot link	[7]
Baihui	GV20	GSDMD	Uniprot link	[7]
Baihui	GV20	SLC2A1	Uniprot link	[20]
Baihui	GV20	SLC2A3	Uniprot link	[20]
Baihui	GV20	SLC2A4	Uniprot link	[20]
Baihui	GV20	AQP4	Uniprot link	[21]
Baihui	GV20	AIF1	Uniprot link	[13]
Baihui	GV20	CD36	Uniprot link	[22]
Baihui	GV20	HMOX1	Uniprot link	[22]
Baihui	GV20	CAMK2G	Uniprot link	[23]
Baihui	GV20	MAPT	Uniprot link	[23]
Baihui	GV20	CAMK4	Uniprot link	[23]
Baihui	GV20	BDNF	Uniprot link	[14,24-28]
Baihui	GV20	HSPA4	Uniprot link	[14]
Baihui	GV20	MAPT	Uniprot link	[29]
Baihui	GV20	MAPT	Uniprot link	[29]
Baihui	GV20	SLC2A1	Uniprot link	[29]
Baihui	GV20	SLC2A3	Uniprot link	[29]
Baihui	GV20	SLC2A4	Uniprot link	[29]
Baihui	GV20	INSR	Uniprot link	[29]
Baihui	GV20	PIK3C3	Uniprot link	[29]
Baihui	GV20	AKT2	Uniprot link	[29]
Baihui	GV20	PIK3C3	Uniprot link	[30]
Baihui	GV20	AKT2	Uniprot link	[30]
Baihui	GV20	BCL2	Uniprot link	[30-31]
Baihui	GV20	HTR5A	Uniprot link	[24,32]
Baihui	GV20	CAMP	Uniprot link	[24]
Baihui	GV20	RAP1B	Uniprot link	[24]
Baihui	GV20	MAP3K3	Uniprot link	[24]
Baihui	GV20	MAPK3	Uniprot link	[24]
Baihui	GV20	CREB1	Uniprot link	[24]
Baihui	GV20	PIK3C3	Uniprot link	[33]
Baihui	GV20	AKT2	Uniprot link	[33]
Baihui	GV20	CASP3	Uniprot link	[33-35]
Baihui	GV20	TJP1	Uniprot link	[8]
Baihui	GV20	HSPA8	Uniprot link	[8]
Baihui	GV20	TLR4	Uniprot link	[8]
Baihui	GV20	SYT1	Uniprot link	[8]
Baihui	GV20	IL1B	Uniprot link	[8,12]
Baihui	GV20	DAO	Uniprot link	[8]
Baihui	GV20	S100B	Uniprot link	[8]
Baihui	GV20	AIF1	Uniprot link	[8]
Baihui	GV20	CCL4	Uniprot link	[36]
Baihui	GV20	SYT1	Uniprot link	[36]
Baihui	GV20	NOS2	Uniprot link	[36]
Baihui	GV20	HTR5A	Uniprot link	[36]
Baihui	GV20	LEMD2	Uniprot link	[36]
Baihui	GV20	AQP1	Uniprot link	[37]
Baihui	GV20	EPHA8	Uniprot link	[38]
Baihui	GV20	BAX	Uniprot link	[31]
Baihui	GV20	HTR5A	Uniprot link	[32]
Baihui	GV20	SOD3	Uniprot link	[32]
Baihui	GV20	KEAP1	Uniprot link	[32]
Baihui	GV20	HMOX1	Uniprot link	[32]
Baihui	GV20	SLC6A3	Uniprot link	[39]
Baihui	GV20	HTR5A	Uniprot link	[39]
Baihui	GV20	SOCS3	Uniprot link	[40]
Baihui	GV20	JAK2	Uniprot link	[40]
Baihui	GV20	STAT3	Uniprot link	[40]
Baihui	GV20	IL4	Uniprot link	[11,41]
Baihui	GV20	IL10	Uniprot link	[41]
Baihui	GV20	GJA1	Uniprot link	[42]
Baihui	GV20	NLRP3	Uniprot link	[12]
Baihui	GV20	PYCARD	Uniprot link	[12]
Baihui	GV20	CARD17	Uniprot link	[12]
Baihui	GV20	C1QTNF3	Uniprot link	[43]
Baihui	GV20	GJA1	Uniprot link	[34]
Baihui	GV20	APPBP2	Uniprot link	[44]
Baihui	GV20	PSORS1C2	Uniprot link	[44]
Baihui	GV20	RHOA	Uniprot link	[45]
Baihui	GV20	ROCK2	Uniprot link	[45]
Baihui	GV20	RPP38	Uniprot link	[46]
Baihui	GV20	GFAP	Uniprot link	[47]
Baihui	GV20	NF1	Uniprot link	[47]
Baihui	GV20	IGF1R	Uniprot link	[48]
Baihui	GV20	GSK3B	Uniprot link	[48]
Baihui	GV20	IL1A	Uniprot link	[9]
Baihui	GV20	ACE2	Uniprot link	[49]
Baihui	GV20	ANGPT2	Uniprot link	[49]
Baihui	GV20	CAT	Uniprot link	[50]
Baihui	GV20	LUC7L3	Uniprot link	[51]
Baihui	GV20	MAPKAPK2	Uniprot link	[52]
Baihui	GV20	NGB	Uniprot link	[52]
Baihui	GV20	NGF	Uniprot link	[26]
Baihui	GV20	EIF4ENIF1	Uniprot link	[15]
Baihui	GV20	NSMCE2	Uniprot link	[15]
Baihui	GV20	TLR4	Uniprot link	[53]
Baihui	GV20	P2RX7	Uniprot link	[54]
Baihui	GV20	KEAP1	Uniprot link	[55]
Baihui	GV20	HMOX1	Uniprot link	[55]
Baihui	GV20	NQO1	Uniprot link	[55]
Baihui	GV20	CCL5	Uniprot link	[56]
Baihui	GV20	ZC3H12A	Uniprot link	[56]
Baihui	GV20	CXCR3	Uniprot link	[56]
Baihui	GV20	iga	Uniprot link	[57]
Baihui	GV20	TBX21	Uniprot link	[57]
Baihui	GV20	ERN1	Uniprot link	[58]
Baihui	GV20	HM13	Uniprot link	[58]
Baihui	GV20	NAA80	Uniprot link	[27]
Baihui	GV20	NUAK2	Uniprot link	[27]
Baihui	GV20	MIF4GD	Uniprot link	[27]
Baihui	GV20	NTRK2	Uniprot link	[27]
Baihui	GV20	NAA35	Uniprot link	[59]
Baihui	GV20	PRKCSH	Uniprot link	[59]
Baihui	GV20	HSPA5	Uniprot link	[60]
Baihui	GV20	CASP12	Uniprot link	[60]
Baihui	GV20	HIF1AN	Uniprot link	[61]
Baihui	GV20	IL1B	Uniprot link	[17]
Baihui	GV20	IL10	Uniprot link	[17]
Baihui	GV20	CORT	Uniprot link	[62]
Baihui	GV20	ACTG2	Uniprot link	[62]
Baihui	GV20	LINGO1	Uniprot link	[63]
Baihui	GV20	CAMK2B	Uniprot link	[64]
Baihui	GV20	GJA1	Uniprot link	[65]
Baihui	GV20	CORT	Uniprot link	[66]
Baihui	GV20	ACTG2	Uniprot link	[66]
Baihui	GV20	S100B	Uniprot link	[67]
Baihui	GV20	TP53	Uniprot link	[68]
Baihui	GV20	NTRK2	Uniprot link	[28]
Baihui	GV20	FAM83A	Uniprot link	[69]
Baihui	GV20	JAK2	Uniprot link	[70]
Baihui	GV20	STAT3	Uniprot link	[70]
Baihui	GV20	ASCC1	Uniprot link	[18]
Baihui	GV20	NOS2	Uniprot link	[18]
Baihui	GV20	TRADD	Uniprot link	[18]
Baihui	GV20	FADD	Uniprot link	[18]
Baihui	GV20	NR1D1	Uniprot link	[71]
Baihui	GV20	HIF1A	Uniprot link	[72]
Baihui	GV20	EPO	Uniprot link	[72]
Baihui	GV20	IL5RA	Uniprot link	[72]
Baihui	GV20	EPOR	Uniprot link	[72]
Baihui	GV20	HSPBP1	Uniprot link	[72]
Baihui	GV20	BAX	Uniprot link	[35,72]
Baihui	GV20	BCL2	Uniprot link	[72]
Baihui	GV20	CD34	Uniprot link	[73]
Baihui	GV20	VEGFB	Uniprot link	[73]
Baihui	GV20	FGF2	Uniprot link	[73]
Baihui	GV20	NLRP3	Uniprot link	[74]
Baihui	GV20	NOS2	Uniprot link	[11]
Baihui	GV20	ARG1	Uniprot link	[11]
Baihui	GV20	IL1B	Uniprot link	[11]
Baihui	GV20	IL10	Uniprot link	[11]
Baihui	GV20	SYT1	Uniprot link	[11]
Baihui	GV20	STAT6	Uniprot link	[11]
Baihui	GV20	CAMK4	Uniprot link	[75]
Baihui	GV20	FGFR1	Uniprot link	[76]
Baihui	GV20	PIK3C2B	Uniprot link	[77]
Baihui	GV20	AKT1	Uniprot link	[77]
Baihui	GV20	RHOA	Uniprot link	[78]
Baihui	GV20	ROCK2	Uniprot link	[78]
Baihui	GV20	BCL2	Uniprot link	[35]
Baihui	GV20	CLOCK	Uniprot link	[35]
Baihui	GV20	ARNTL	Uniprot link	[35]
Baihui	GV20	SYN3	Uniprot link	[79]
Baihui	GV20	GSK3A	Uniprot link	[79]
Baihui	GV20	MTOR	Uniprot link	[79]
Baihui	GV20	CREB1	Uniprot link	[25]

[1] 许文婷, 薛玉满, 王策,等. 百会透曲鬓调控EGFR/STAT3通路抑制脑出血大鼠神经功能损伤的机制研究[J]. 针灸临床杂志,2022,38(07):70-75.

[2] 郭文海, 颜敬彧, 邢菁,等. “原络通经”针法对SAMP8小鼠病理形态学及NMDAR表达的影响[J]. 针灸临床杂志,2022,38(06):69-74.

[3] 徐佳, 陈奥, 史珊怡,等. “原络通经”针法调节痴呆小鼠肠道菌群微生态及肠道SCFA代谢的机制研究[J]. 辽宁中医药大学学报,:1-11.

[4] 王婧吉, 瞿艳, 王娟,等. 电针“百会”“神庭”对血管性痴呆大鼠学习记忆能力和海马突触结构与相关蛋白表达水平的影响[J]. 安徽中医药大学学报,2022,41(03):51-56.

[5] 张洋, 谭韵湘, 高誉珊,等. 电针“百会”“涌泉”对6月龄APP/PS1双转基因小鼠行为学及海马Dynein、CTSD水平影响的研究[J]. 针灸临床杂志,2022,38(04):67-73.

[6] 刘丹妮, 周君, 黄夏荣,等. 电针“水沟”“百会”穴对脑缺血再灌注损伤大鼠海马神经元自噬的影响[J]. 针刺研究,2022,47(06):491-496.

[7] 罗敷, 封蔚彬, 刘丹妮,等. 电针“百会“”人中”对脑缺血再灌注损伤模型大鼠脑脊液炎症因子及皮质缺血区脑组织GSDMD表达的影响[J]. 中医杂志,2022,63(02):164-168.

[8] 何川. “标本配穴”预针刺调控肠道菌群-LPS-神经炎性反应对衰老模型大鼠学习记忆认知功能障碍的机制研究[D] :湖北中医药大学,2021.

[9] 赵秋阳, 马贤德. 针刺百会、四神聪对MCAO模型大鼠缺血半暗带脑组织中IL-1、IL-6、TNF-α的影响[J]. 中国康复,2019,34(03):115-118.

[10] 刘倩, 黄银兰, 薛小卫,等. 针刺百会穴对癫痫大鼠行为学、体质量及IL-6表达的影响[J]. 中华中医药学刊,2018,36(02):299-302.

[11] Xie L, Liu Y, Zhang N, et al. Electroacupuncture Improves M2 Microglia Polarization and Glia Anti-inflammation of Hippocampus in Alzheimer’s Disease[J]. Front Neurosci, 2021,15:689629.

[12] 石国旗. 电针神庭百会对PS cDKO小鼠的学习记忆改善作用及机制研究[D] :广州中医药大学,2020.

[13] 陈小梅, 庞莉娜, 王志福. 电针百会、神庭对系统炎症诱导认知功能障碍的海马抗炎作用[J]. 康复学报,2021,31(05):415-419+424.

[14] 温婧, 陈新旺, 任珊. 艾灸风池、百会穴对脑梗死后大鼠脑神经功能及海马BDNF表达的影响[J]. 中国中医药现代远程教育,2021,19(14):143-146.

[15] 刘益兵, 白玉, 赵祯,等. 温针百会穴联合调气活血法对椎动脉型颈椎病血流动力学及血清TNF-α、ET、NSE的影响研究[J]. 针灸临床杂志,2018,34(07):13-17.

[16] 谢璐霜, 余曙光, 吴巧凤,等. 针灸百会穴对AD模型鼠中枢小胶质细胞TNFα的影响[J]. 四川解剖学杂志,2017,25(01):14-15.

[17] 王宏法, 胡双飞, 王均炉.百会穴腺苷A1受体激动剂注射对创伤性颅脑损伤大鼠脑水含量及炎症介质的影响[A].其他:浙江省人民医院医院麻醉科;温州医学院附属第一医院麻醉科,2015.

[18] Cheng CY, Lin JG, Tang NY, et al. Electroacupuncture-like stimulation at the Baihui (GV20) and Dazhui (GV14) acupoints protects rats against subacute-phase cerebral ischemia-reperfusion injuries by reducing S100B-mediated neurotoxicity[J]. PLoS One, 2014,9(3):e91426.

[19] 李鹏飞, 任俊华, 苏滑,等. 百会、神庭电针干预对脑卒中大鼠认知功能的改善及对血管新生相关因子eNOS、NO表达的影响[J]. 针灸临床杂志,2022,38(02):74-79.

[20] 武峻艳, 李星, 王杰,等. 针刺百会、水沟对AD大鼠海马区GLUT1、3、4的影响[J]. 时珍国医国药,2021,32(12):3060-3063.

[21] 陈镜竹. 艾灸和电针刺激“百会”穴对小鼠胶质淋巴系统功能的影响[D] :成都中医药大学,2021.

[22] 陈秋欣, 孔莹, 于婷婷,等. 针刺“百会”透“曲鬓”穴对急性脑出血大鼠血肿及CD36、HO-1表达的影响[J]. 针灸临床杂志,2021,37(08):59-63.

[23] 王志杰, 王永超, 杨敏,等. 电针百会穴对次声暴露大鼠学习记忆能力及其钙调素依赖性蛋白激酶Ⅱ-Tau蛋白信号通路的影响[J]. 中华物理医学与康复杂志,2021,43(07):595-601.

[24] 曹灵修. 肾阳虚型抑郁症“穴位敏化”研究及“温肾通督”针法对RAP1信号通路影响[D] :辽宁中医药大学,2021.

[25] Lee B, Sur B, Shim J, et al. Acupuncture stimulation improves scopolamine-induced cognitive impairment via activation of cholinergic system and regulation of BDNF and CREB expressions in rats[J]. BMC Complement Altern Med, 2014,14:338.

[26] 刘启, 梁丹丹, 许伶,等. 针刺百会穴、风府穴对脑缺血损伤大鼠神经功能及NGF、BDNF表达的影响[J]. 河南中医,2018,38(08):1168-1171.

[27] 张颖铮. 电针“百会”穴对APP/PS1双转基因小鼠海马区代谢物及空间学习记忆能力的影响[D] :福建中医药大学,2017.

[28] Xu X, Zheng P, Zhao H, et al. Effect of Electroacupuncture at GV20 on Sleep Deprivation-Induced Depression-Like Behavior in Mice[J]. Evid Based Complement Alternat Med, 2020,2020:7481813.

[29] 李星. 基于PI3K/AKT信号通路探讨针刺对AD大鼠海马区葡萄糖代谢的影响机制[D] :山西中医药大学,2021.

[30] 高邈, 凌波, 覃旭. 电针百会和四神聪对缺血再灌注损伤模型鼠学习记忆能力及细胞凋亡的影响[J]. 世界中医药,2021,16(08):1226-1230.

[31] 刘芳, 余李强, 聂平英,等. 艾灸百会穴对MCAO大鼠学习记忆能力及海马Bcl-2、Bax的影响[J]. 长治医学院学报,2021,35(01):1-5.

[32] 崔友祥, 王洪亮, 刘国华,等. 百会穴加强扬刺对中风后抑郁患者抗氧化酶及Nrf2/HO-1通路的影响[J]. 中医药学报,2021,49(02):37-41.

[33] 刘静. 探讨运动针刺干预激活PI3K-AKT信号通路对VaD神经元保护及Caspase-3表达影响的研究[D] :广西中医药大学,2021.

[34] 郑梦雨. 针刺对脑缺血再灌注大鼠GAP-43和Caspase-3表达水平的影响[D] :辽宁中医药大学,2020.

[35] Xu XY, Fang Q, Huang W, et al. Effect of Electroacupuncture on Neurological Deficit and Activity of Clock and Bmal1 in Cerebral Ischemic Rats[J]. Curr Med Sci, 2020,40(6):1128-1136.

[36] 王洪亮, 胡方梅, 刘国华,等. 加强扬刺百会对中风后抑郁病人MIP-1α和NF-κB/iNOS/NO信号通路的影响[J]. 中西医结合心脑血管病杂志,2021,19(07):1184-1188.

[37] 郝多丽, 李航, 董瑞娟,等. 砭贴百会、内关穴对急性低压缺氧大鼠心肌组织水通道蛋白-1表达的影响[J]. 中华中医药杂志,2021,36(04):2363-2366.

[38] 高东升, 杨晓燕, 马临庆,等. 电针百会和大椎穴对癫痫大鼠海马CA3和DG区ephrinA5表达的影响[J]. 国际神经病学神经外科学杂志,2021,48(01):50-54.

[39] 黄秀容, 袁青, 柳爱红,等. 针刺百会、印堂对脑卒中抑郁大鼠神经递质释放及miRNA-219/CaMKⅡγ通路的影响[J]. 针灸临床杂志,2020,36(12):63-68.

[40] 刘静, 胡佳, 王薇,等. 针灸百会、肾俞穴对AD模型大鼠JAK-STAT信号通路影响的实验研究 :武汉市中医医院,2020.

[41] 郑宇, 张露芬, 王春生,等. 针刺不同穴位对慢性炎症痛模型大鼠血清IL-4及IL-10的影响[J]. 西部中医药,2020,33(08):30-33.

[42] 惠建荣, 羊璞, 赵娴,等. 电针结合传统针刺百会、大椎穴对脑缺血模型大鼠GAP-43表达的影响[J]. 陕西中医,2020,41(07):856-859.

[43] 温鑫. 针刺“百会”透“曲鬓”对脑出血急性期大鼠脑中CTRP3含量的影响[D] :黑龙江中医药大学,2020.

[44] 张冰雪. 电针激活AMPK调控有氧糖酵解影响APP/PS1转基因小鼠学习记忆能力的机制研究[D] :福建中医药大学,2020.

[45] 陈素辉. 电针百会、足三里对脑缺血再灌注损伤大鼠髓鞘相关抑制因子介导的RhoA/ROCK神经再生通路的影响[D] :北京协和医学院,2020.

[46] 孔莹, 孔菲, 王子微,等. 针刺“百会”透“曲鬓”对JNK通路抑制后脑出血大鼠脑组织p38MAPK的影响[J]. 中国中医急症,2019,28(10):1705-1707+1711.

[47] 杨超, 程红亮, 胡培佳,等. 电针百会、风府对血管性痴呆大鼠海马CA1区GFAP与NF表达的影响[J]. 时珍国医国药,2019,30(07):1776-1778.

[48] 吴萍萍. 益髓灸对APP/PS1双转基因小鼠海马组织及脑组织IGF-1、GSK-3β蛋白表达的影响[D] :广西中医药大学,2019.

[49] 王紫娟, 纪智, 袁静云,等. 电针“百会”“太冲”对自发性高血压大鼠主动脉Ang Ⅱ、Ang(1-7)蛋白表达的影响[J]. 中国中医急症,2019,28(03):402-405.

[50] 金毅轩. 针刺结合活络聪明汤对老年健忘大鼠T-AOC及CAT的影响[D] :辽宁中医药大学,2019.

[51] 裴亚妮, 杨光, 张磊,等. 电针“百会”“涌泉”对4月龄APP/PS1双转基因小鼠海马LC3和Aβ影响的研究[J]. 世界科学技术-中医药现代化,2019,21(02):307-312.

[52] 郑述铭, 林新锋, 杨莉,等. 基于p38 MAPK信号通路探讨电针百会、水沟穴对脓毒性脑病大鼠的脑保护作用[J]. 上海中医药大学学报,2018,32(05):73-77.

[53] 王卉. 针刺“百会”透“曲鬓”对脑出血急性期大鼠血清中TLR4含量的影响[D] :黑龙江中医药大学,2018.

[54] 宋长明. 电针脑缺血再灌注大鼠“百会”“神庭”穴调控海马P2X7受体影响突触可塑性的机制研究[D] :福建中医药大学,2018.

[55] 戴晓红. 基于Nrf2-ARE信号通路研究“百会”透“曲鬓”对脑出血大鼠的脑保护作用[D] :黑龙江中医药大学,2018.

[56] 刘倩, 黄银兰, 薛小卫,等. 液相芯片技术检测癫痫大鼠海马组织RANTES、MCP-1、IP-10的表达研究[J]. 辽宁中医杂志,2018,45(05):1062-1065.

[57] 刘倩, 黄银兰, 薛小卫,等. 针刺百会穴对氯化锂-匹鲁卡品诱发癫痫大鼠海马组织IgA、IgG2a表达的影响[J]. 中华中医药杂志,2018,33(03):1089-1091.

[58] 肖飞, 张高峰, 尹曾,等. 电针预处理对脑缺血再灌注大鼠皮层内质网IRE1-XBP1信号通路的影响[J]. 中华麻醉学杂志,2018,38(02):226-229.

[59] 张颖铮, 卓沛元, 林如辉,等. 电针百会穴改善APP/PS1转基因小鼠空间学习记忆能力及对磁共振波谱的影响[J]. 康复学报,2016,26(05):42-46.

[60] 沈菁, 雷晓明, 宋洋,等. 电针内关、百会穴对脑缺血/再灌注大鼠GRP78和Caspase-12基因表达的影响[J]. 湖南中医药大学学报,2016,36(02):54-57.

[61] 徐浩, 沈剑, 赵昱,等. 电针预处理大鼠百会穴对脑缺血保护作用及HIF-1α相关机制的研究[J]. 神经解剖学杂志,2015,31(05):617-622.

[62] 高双金, 韦红巧, 李炳,等. 电针百会穴对获得性无助大鼠抑郁样行为和血清CORT及ACTH的影响[J]. 现代医药卫生,2013,29(13):1921-1923.

[63] 钟艺华, 李光勤, 唐显军,等. 电针对局灶性脑梗死大鼠神经功能及LINGO1表达的穴位比较研究[J]. 中国康复医学杂志,2012,27(05):410-414+427.

[64] 张全爱, 林咸明, 孙晓慧,等. 艾灸百会穴对AD大鼠学习记忆能力及海马区CaMKⅡ mRNA表达的影响[J]. 上海中医药大学学报,2011,25(05):86-88.

[65] 廖丛, 周江堡, 胡文静,等. 聚焦超声辐照百会穴对HIBD大鼠的神经康复作用[J]. 中国超声医学杂志,2011,27(07):591-594.

[66] 陈华德, 金灵青, 娄冉,等. 百会穴电针和埋线对慢性应激抑郁模型大鼠行为学及血清CORT和ACTH的影响[J]. 上海针灸杂志,2010,29(04):244-247.

[67] 霍丽. 电针“百会”穴对轻度认知功能障碍模型大鼠学习记忆能力及脑内S100β蛋白表达的影响[D] :辽宁中医药大学,2008.

[68] Guan R, Li Z, Dai X, et al. Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis[J]. Mol Med Rep, 2021,24(1)

[69] Zhang X, Qiu H, Li C, et al. The positive role of traditional Chinese medicine as an adjunctive therapy for cancer[J]. Biosci Trends, 2021,15(5):283-298.

[70] Xu H, Zhang YM, Sun H, et al. Electroacupuncture at GV20 and ST36 Exerts Neuroprotective Effects via the EPO-Mediated JAK2/STAT3 Pathway in Cerebral Ischemic Rats[J]. Evid Based Complement Alternat Med, 2017,2017:6027421.

[71] Lin YW, Hsieh CL. Electroacupuncture at Baihui acupoint (GV20) reverses behavior deficit and long-term potentiation through N-methyl-d-aspartate and transient receptor potential vanilloid subtype 1 receptors in middle cerebral artery occlusion rats[J]. J Integr Neurosci, 2010,9(3):269-282.

[72] Liu F, Lu Z, Li Z, et al. Electroacupuncture Improves Cerebral Ischemic Injury by Enhancing the EPO-JAK2-STAT5 Pathway in Rats[J]. Neuropsychiatr Dis Treat, 2021,17:2489-2498.

[73] Yang L, Yang BC, Zhang CX, et al. Protective effects of acupuncture and LGNHFD on expressions of vascular endothelial growth factor, basic fibroblast growth factor, and cluster of differentiation 34 in rats with cerebral ischemia-reperfusion injury[J]. J Tradit Chin Med, 2021,41(3):463-470.

[74] Li X, Wang H, Li C, et al. Acupuncture inhibits NLRP3 inflammasome activation in the prefrontal cortex of a chronic stress rat model of depression[J]. Anat Rec (Hoboken), 2021,304(11):2470-2479.

[75] Bai L, Zhang D, Cui TT, et al. Mechanisms Underlying the Antidepressant Effect of Acupuncture via the CaMK Signaling Pathway[J]. Front Behav Neurosci, 2020,14:563698.

[76] Yao Z, Zhang Z, Zhang J, et al. Electroacupuncture alleviated the depression-like behavior by regulating FGF2 and astrocytes in the hippocampus of rats with chronic unpredictable mild stress[J]. Brain Res Bull, 2021,169:43-50.

[77] Wang HL, Liu FL, Li RQ, et al. Electroacupuncture improves learning and memory functions in a rat cerebral ischemia/reperfusion injury model through PI3K/Akt signaling pathway activation[J]. Neural Regen Res, 2021,16(6):1011-1016.

[78] Zhu MM, Lin JH, Qing P, et al. Manual acupuncture relieves microglia-mediated neuroinflammation in a rat model of traumatic brain injury by inhibiting the RhoA/ROCK2 pathway[J]. Acupunct Med, 2020,38(6):426-434.

[79] Yu CC, Wang J, Ye SS, et al. Preventive Electroacupuncture Ameliorates D-Galactose-Induced Alzheimer’s Disease-Like Pathology and Memory Deficits Probably via Inhibition of GSK3β/mTOR Signaling Pathway[J]. Evid Based Complement Alternat Med, 2020,2020:1428752.